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The project REBOOT protocol: Evaluating a personalized inhibitory control training as an adjunct to cognitive behavioral therapy for bulimia nervosa and binge-eating disorder
Journal article   Open access   Peer reviewed

The project REBOOT protocol: Evaluating a personalized inhibitory control training as an adjunct to cognitive behavioral therapy for bulimia nervosa and binge-eating disorder

Stephanie M. Manasse, Elizabeth W. Lampe, Lindsay Gillikin, Adam Payne-Reichert, Fengqing Zhang, Adrienne S. Juarascio and Evan M. Forman
The International journal of eating disorders, v 53(6), pp 1007-1013
01 Jun 2020
PMID: 32221989
url
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283009View
Accepted (AM)Open Access (License Unspecified) Open

Abstract

Life Sciences & Biomedicine Nutrition & Dietetics Psychiatry Psychology Psychology, Clinical Science & Technology Social Sciences
Outcomes from cognitive behavioral therapy (CBT) for bulimia nervosa (BN) and binge-eating disorder (BED) are suboptimal. One potential explanation is that CBT fails to adequately target inhibitory control (i.e., the ability to withhold an automatic response), which is a key maintenance factor for binge eating. Computerized inhibitory control training (ICT) is a promising method for improving inhibitory control but is relatively untested in BN/BED. The present study will evaluate a computer-based ICT as an adjunct to CBT for BN/BED. Participants with BN (n = 30) or BED (n = 30) will be randomized to 12 weeks of either CBT + ICT or CBT + a sham training. Trainings will be completed daily for 4 weeks and weekly for 8 weeks. Primary aims include the following: (a) confirm target engagement (evaluate whether ICT improves inhibitory control), (b) test target validation (evaluate whether improvements in inhibitory control are associated with improvements in binge eating), and (c) evaluate the incremental efficacy of ICT on binge eating. Secondary aims include the following: (a) evaluate ICT feasibility and acceptability and (b) assess the moderating effects of approach tendencies on highly palatable food, dietary restraint, and diagnosis. Data will be used to shape a fully powered clinical trial designed to assess efficacy and dose-response effects of ICT for BN/BED.

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Web of Science research areas
Nutrition & Dietetics
Psychiatry
Psychology
Psychology, Clinical
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