The project REBOOT protocol: Evaluating a personalized inhibitory control training as an adjunct to cognitive behavioral therapy for bulimia nervosa and binge-eating disorder
Life Sciences & Biomedicine Nutrition & Dietetics Psychiatry Psychology Psychology, Clinical Science & Technology Social Sciences
Outcomes from cognitive behavioral therapy (CBT) for bulimia nervosa (BN) and binge-eating disorder (BED) are suboptimal. One potential explanation is that CBT fails to adequately target inhibitory control (i.e., the ability to withhold an automatic response), which is a key maintenance factor for binge eating. Computerized inhibitory control training (ICT) is a promising method for improving inhibitory control but is relatively untested in BN/BED. The present study will evaluate a computer-based ICT as an adjunct to CBT for BN/BED. Participants with BN (n = 30) or BED (n = 30) will be randomized to 12 weeks of either CBT + ICT or CBT + a sham training. Trainings will be completed daily for 4 weeks and weekly for 8 weeks. Primary aims include the following: (a) confirm target engagement (evaluate whether ICT improves inhibitory control), (b) test target validation (evaluate whether improvements in inhibitory control are associated with improvements in binge eating), and (c) evaluate the incremental efficacy of ICT on binge eating. Secondary aims include the following: (a) evaluate ICT feasibility and acceptability and (b) assess the moderating effects of approach tendencies on highly palatable food, dietary restraint, and diagnosis. Data will be used to shape a fully powered clinical trial designed to assess efficacy and dose-response effects of ICT for BN/BED.
The project REBOOT protocol: Evaluating a personalized inhibitory control training as an adjunct to cognitive behavioral therapy for bulimia nervosa and binge-eating disorder
Creators
Stephanie M. Manasse - Drexel University
Elizabeth W. Lampe - Drexel University
Lindsay Gillikin - Drexel University
Adam Payne-Reichert - Drexel University
Fengqing Zhang - Drexel University
Adrienne S. Juarascio - Drexel University
Evan M. Forman - Drexel University
Publication Details
The International journal of eating disorders, v 53(6), pp 1007-1013
Publisher
Wiley
Number of pages
7
Grant note
R34MH118353 / National Institute of Mental Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Mental Health (NIMH)
Resource Type
Journal article
Language
English
Academic Unit
Psychological and Brain Sciences (Psychology); Center for Weight, Eating and Lifestyle Science (WELL) [Historical]
Web of Science ID
WOS:000521807300001
Scopus ID
2-s2.0-85082747137
Other Identifier
991019169622604721
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