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The rate of fusion of phospholipid vesicles and the role of bilayer curvature
Journal article   Peer reviewed

The rate of fusion of phospholipid vesicles and the role of bilayer curvature

Shlomo Nir, Jan Wilschut and Joe Bentz
Biochimica et biophysica acta. Biomembranes, v 688(1), pp 275-278
21 May 1982
PMID: 7093279

Abstract

Bilayer curvature Fusion rate Phospholipid
Kinetics of Ca 2+-induced fusion of phosphatidylserine vesicles is studiied for lipid concentrations varying from 1 μM to 100 μM. Fusion is monitored by mixing of aqueous vesicle contents and by explicitly accounting for leakage. The analysis provides separately rates of aggregation and fusion. The rate of fusion per se decreases steeply with vesicle size.

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Domestic collaboration
International collaboration
Web of Science research areas
Biochemistry & Molecular Biology
Biophysics
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