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Accepted (AM)Open Access (License Unspecified), Open
Journal article
The relationship between long-term sunlight radiation and cognitive decline in the REGARDS cohort study
International journal of biometeorology, v 58(3), pp 361-370
01 Apr 2014
PMCID: PMC3665728
PMID: 23340910
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Sunlight may be related to cognitive function through vitamin D metabolism or circadian rhythm regulation. The analysis presented here sought to test whether ground and satellite measures of solar radiation are associated with cognitive decline. The study used a 15-year residential history merged with satellite and ground monitor data to determine sunlight (solar radiation) and air temperature exposure for a cohort of 19,896 cognitively intact black and white participants aged 45+ from the 48 contiguous United States. Exposures of 15, 10, 5, 2, and 1-year were used to predict cognitive status at the most recent assessment in logistic regression models; 1-year insolation and maximum temperatures were chosen as exposure measures. Solar radiation interacted with temperature, age, and gender in its relationships with incident cognitive impairment. After adjustment for covariates, the odds ratio (OR) of cognitive decline for solar radiation exposure below the median vs above the median in the 3rd tertile of maximum temperatures was 1.88 (95 % CI: 1.24, 2.85), that in the 2nd tertile was 1.33 (95 % CI: 1.09, 1.62), and that in the 1st tertile was 1.22 (95 % CI: 0.92, 1.60). We also found that participants under 60 years old had an OR = 1.63 (95 % CI: 1.20, 2.22), those 60-80 years old had an OR = 1.18 (95 % CI: 1.02, 1.36), and those over 80 years old had an OR = 1.05 (0.80, 1.37). Lastly, we found that males had an OR = 1.43 (95 % CI: 1.22, 1.69), and females had an OR = 1.02 (0.87, 1.20). We found that lower levels of solar radiation were associated with increased odds of incident cognitive impairment.
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Details
- Title
- The relationship between long-term sunlight radiation and cognitive decline in the REGARDS cohort study
- Creators
- Shia T. Kent - University of Alabama at BirminghamEdmond K. Kabagambe - University of Alabama at BirminghamVirginia G. Wadley - University of Alabama at BirminghamVirginia J. Howard - University of Alabama at BirminghamWilliam L. Crosson - Marshall Space Flight CenterMohammad Z. Al-Hamdan - Marshall Space Flight CenterSuzanne E. Judd - University of Alabama at BirminghamFredrick Peace - Univ Alabama Birmingham, Dept Biostat, Sch Publ Hlth, Birmingham, AL 35294 USALeslie A. McClure - University of Alabama at Birmingham
- Publication Details
- International journal of biometeorology, v 58(3), pp 361-370
- Publisher
- Springer Nature
- Number of pages
- 10
- Grant note
- U01 NS041588 / National Institute of Neurological Disorders and Stroke; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS) NNX09AV81G / National Aeronautics and Space Administration; National Aeronautics & Space Administration (NASA) U01NS041588 / NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Epidemiology and Biostatistics
- Web of Science ID
- WOS:000333120100006
- Scopus ID
- 2-s2.0-84896402698
- Other Identifier
- 991019231735504721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Biophysics
- Environmental Sciences
- Meteorology & Atmospheric Sciences
- Physiology