Journal article
The systemic lupus erythematosus Tri-Nation study: cumulative indirect costs
Arthritis and rheumatism, v 57(1), pp 64-70
15 Feb 2007
PMID: 17266095
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
OBJECTIVEWe previously reported that patients with systemic lupus erythematosus (SLE) in the US incurred approximately 19% and 12% higher direct medical costs than patients in Canada and the UK, respectively, without experiencing superior outcomes expressed as disease damage or quality of life. In the present study, we compared cumulative indirect costs over 4 years in these patients.METHODSA total of 715 patients with SLE (269 US, 231 Canada, 215 UK) were surveyed semiannually for 4 years on employment status and time lost from labor and nonlabor market activities. Cross-country comparisons of indirect costs were performed.RESULTSIn the US, Canada, and the UK, mean 4-year cumulative indirect costs (95% confidence interval [95% CI]) due to diminished labor market activity were $56,745 ($49,919, $63,571), $38,642 ($32,785, $44,500), and $42,213 ($35,859, $48,567), respectively, and cumulative indirect costs due to diminished nonlabor market activity were $5,249 ($2,766, $7,732), $5,455 ($3,290, $7,620), and $8,572 ($5,626, $11,518), respectively. Regression results showed that cumulative indirect costs (95% CI) due to diminished labor market activity in the US were $6,750 ($580, $12,910) greater than in Canada and $10,430 ($4,050, $16,800) greater than in the UK. Indirect costs due to diminished nonlabor market activity in the US were $280 (-$2,950, $3,520) less than in Canada and $2,010 (-$1,490, $5,510) less than in the UK, both results insignificant due to wide CIs.CONCLUSIONDespite American patients incurring greater direct medical costs than Canadian and British patients, they do not experience superior health outcomes in terms of less productivity loss in either labor market or nonlabor market activities.
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Details
- Title
- The systemic lupus erythematosus Tri-Nation study: cumulative indirect costs
- Creators
- Pantelis Panopalis - McGill UniversityMichelle Petri - Johns Hopkins MedicineSusan Manzi - University of PittsburghDavid A Isenberg - University College LondonCaroline Gordon - University of BirminghamJean-Luc SenécalJohn R Penrod - McGill UniversityLawrence Joseph - McGill UniversityYvan St PierreChristian Pineau - McGill UniversityPaul R tinNurhan Sutcliffe - University College LondonJean-Richard GouletDenis Choquette - Université de MontréalTamara Grodzicky - Université de MontréalJohn M Esdaile - University of British ColumbiaAnn E Clarke - McGill UniversityTri-Nation Study Grp
- Publication Details
- Arthritis and rheumatism, v 57(1), pp 64-70
- Publisher
- Wiley
- Number of pages
- 7
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- General Internal Medicine
- Web of Science ID
- WOS:000244138100010
- Scopus ID
- 2-s2.0-33846949359
- Other Identifier
- 991021934005304721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Rheumatology