Journal article
The systemic lupus erythematosus tri-nation study: longitudinal changes in physical and mental well-being
Rheumatology (Oxford, England), v 44(6), pp 751-755
01 Jun 2005
PMID: 15757968
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Objective. We have shown that SLE patients in Canada and the UK incurred 20% and 13% lower health costs than those in the US, respectively, but did not experience worse outcomes as expressed by the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index. We now compare change in quality of life in these patients. Patients and methods. Seven hundred and fifteen SLE patients (Canada 231, US 269, UK 215) completed the SF-36 annually over four years. The annual change in the SF-36 Physical and Mental Component Summary (PCS and MCS) scores over the course of the study were summarized by estimating a linear trend for each individual patient using hierarchical modelling. Cross-country comparison of the slopes in the PCS and MCS scores was then performed using simultaneous regressions. Results. The estimated mean annual changes (95% credible interval [CrI]) in the PCS scores in Canada, the US, and the UK were 0.18 (−0.07, 0.43), −0.05 (−0.27, 0.17), and 0.03 (−0.20, 0.27), respectively; the mean annual changes in the MCS scores were 0.15 (−0.04, 0.34), 0.23 (0.09, 0.37), and 0.08 (−0.10, 0.27), respectively. Regression results showed that the mean annual changes in PCS and MCS scores did not substantially differ across countries. Conclusion. Quality of life remained stable across countries. Despite Canadian and British patients incurring lower health costs, on average, patients experienced similar changes in physical and mental well-being.
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Details
- Title
- The systemic lupus erythematosus tri-nation study: longitudinal changes in physical and mental well-being
- Creators
- P. Panopalis - Montreal General HospitalM. Petri - McGill UniversityS. Manzi - University of PittsburghD. A. Isenberg - UCL AustraliaC. Gordon - University of BirminghamJ.-L. Senecal - Université de MontréalJ. R. Penrod - McGill UniversityL. JosephY. St. PierreC. Pineau - Center for RheumatologyP. R. Fortin - University of TorontoN. Sutcliffe - UCL AustraliaJ.-R. Goulet - Université de MontréalD. Choquette - Université de MontréalT. Grodzicky - Université de MontréalJ. M. Esdaile - University of British ColumbiaA. E. Clarke - McGill UniversityTri-Nation Study Grp
- Publication Details
- Rheumatology (Oxford, England), v 44(6), pp 751-755
- Publisher
- Oxford University Press
- Number of pages
- 5
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- General Internal Medicine
- Web of Science ID
- WOS:000229441400009
- Scopus ID
- 2-s2.0-24944588883
- Other Identifier
- 991021934012604721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Rheumatology