Journal article
The use of ketamine in complex regional pain syndrome: possible mechanisms
Expert review of neurotherapeutics, v 11(5), pp 719-734
01 May 2011
PMID: 21539489
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Complex regional pain syndrome is a neuropathic pain syndrome that is characterized by: severe pain beyond the area of injury; autonomic dysregulation; neurogenic edema; movement disorder; and atrophy and dystrophy. Ketamine is an open-channel NMDA blocker that only acts on those receptors whose Mg2+ block has been lifted. It is effective in the treatment of the syndrome when standard treatments have failed. Different protocols are utilized depending on the severity of illness. There have been no serious ketamine-induced complications from these protocols, owing to careful psychological screening and the liberal use of midazolam and lorazepam to counter any psychomimetic effects and clonidine to block possible 'Olney s lesions.
Metrics
Details
- Title
- The use of ketamine in complex regional pain syndrome: possible mechanisms
- Creators
- Robert J Schwartzman - Drexel UniversityGuillermo M Alexander - Drexel UniversityJohn R Grothusen - Drexel University
- Publication Details
- Expert review of neurotherapeutics, v 11(5), pp 719-734
- Publisher
- Informa Healthcare
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- [Retired Faculty]; Neurology
- Web of Science ID
- WOS:000290834200016
- Scopus ID
- 2-s2.0-79955659334
- Other Identifier
- 991019169529304721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Clinical Neurology
- Pharmacology & Pharmacy