Journal article
Thermoregulatory effects of the specific uptake inhibitor citalopram in maturing mice
General pharmacology, v 14(5), pp 525-527
1983
PMID: 6580256
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Abstract
1.
1. The effects of a single 20 mg/kg dose of citalopram (Lu 10-171) were studied in mice aged 1–10 days.
2.
2. Body temperature measured 2 and 24 hr after treatment was decreased in treated animals as compared with saline injected littermate controls.
3.
3. Two hours after treatment, temperature preference in a thermal gradient was unchanged in animals younger than 6 days; however, in animals 6 days or older, temperature preference was increased as compared with littermate controls.
4.
4. Twenty-four hours after treatment, temperature preference was increased in citalopram-treated animals at all ages tested.
5.
5. The results are discussed in relation to nervous system maturation.
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Details
- Title
- Thermoregulatory effects of the specific uptake inhibitor citalopram in maturing mice
- Creators
- Cecilie Goodrich - Cleveland State University
- Publication Details
- General pharmacology, v 14(5), pp 525-527
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Biology
- Web of Science ID
- WOS:A1983RQ86100008
- Scopus ID
- 2-s2.0-0020619043
- Other Identifier
- 991021229998404721
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- Web of Science research areas
- Pharmacology & Pharmacy