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Journal article
Three-Dimensional Rotation, Twist and Torsion Analyses Using Real-Time 3D Speckle Tracking Imaging: Feasibility, Reproducibility, and Normal Ranges in Pediatric Population
PloS one, v 11(7), e0158679
18 Jul 2016
PMCID: PMC4948847
PMID: 27427968
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Abstract
Background and Objective
The specific aim of this study was to evaluate the feasibility, reproducibility and maturational changes of LV rotation, twist and torsion variables by real-time 3D speckle-tracking echocardiography (RT3DSTE) in children.
Methods
A prospective study was conducted in 347 consecutive healthy subjects (181 males/156 females, mean age 7.12 +/- 5.3 years, and range from birth to 18-years) using RT 3D echocardiography (3DE). The LV rotation, twist and torsion measurements were made off-line using TomTec software. Manual landmark selection and endocardial border editing were performed in 3 planes (apical "2"-, "4"-, and "3"-chamber views) and semi-automated tracking yielded LV rotation, twist and torsion measurements. LV rotation, twist and torsion analysis by RT 3DSTE were feasible in 307 out of 347 subjects (88.5%).
Results
There was no correlation between rotation or twist and age, height, weight, BSA or heart rate, respectively. However, there was statistically significant, but very modest correlation between LV torsion and age (R-2 = 0.036, P<0.001). The normal ranges were defined for rotation and twist in this cohort, and for torsion for each age group. The intra-observer and inter-observer variabilities for apical and basal rotation, twist and torsion ranged from 7.3% +/- 3.8% to 12.3% +/- 8.8% and from 8.8% +/- 4.6% to 15.7% +/- 10.1%, respectively.
Conclusions
We conclude that analysis of LV rotation, twist and torsion by this new RT3D STE is feasible and reproducible in pediatric population. There is no maturational change in rotation and twist, but torsion decreases with age in this cohort. Further refinement is warranted to validate the utility of this new methodology in more sensitive and quantitative evaluation of congenital and acquired heart diseases in children.
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Details
- Title
- Three-Dimensional Rotation, Twist and Torsion Analyses Using Real-Time 3D Speckle Tracking Imaging: Feasibility, Reproducibility, and Normal Ranges in Pediatric Population
- Creators
- Li Zhang - Huazhong University of Science and TechnologyJing Zhang - Huazhong University of Science and TechnologyWei Han - Huazhong University of Science and TechnologyJun Gao - Huazhong University of Science and TechnologyLin He - Huazhong University of Science and TechnologyYali Yang - Huazhong University of Science and TechnologyPing Yin - Huazhong University of Science and TechnologyMingxing Xie - Huazhong University of Science and TechnologyShuping Ge - Drexel University, College of Medicine
- Publication Details
- PloS one, v 11(7), e0158679
- Publisher
- Public Library Science
- Number of pages
- 12
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pediatrics
- Web of Science ID
- WOS:000380169300018
- Scopus ID
- 2-s2.0-84979226372
- Other Identifier
- 991019168616704721
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Cardiac & Cardiovascular Systems