Journal article
Thyroid Stimulating Hormone Response to Thyrotropin in Prepubertal Depression
Journal of the American Academy of Child and Adolescent Psychiatry, v 30(3), pp 398-406
May 1991
PMID: 1905294
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
In an effort to evaluate whether differences exist in the hypothalamic-pituitary-thyroid axis of depressed children, a thyrotropin releasing hormone (TRH) stimulation test was administered to 55 prepubertal subjects who were divided into three groups matched for age and sex: a depressed group (endogenous N = 15, nonendogenous N = 15), a psychiatric nondepressed control group (N = 16), and a normal control group (N = 9). Each subject was tested at two dosages of TRH, 2 μg/kg and 7 μg/kg. Increasing age and female sex were positively correlated with a greater thyroid stimulating hormone (TSH) response. TSH response to TRH was examined with subjects reclassified by severe suicidal ideation, severe aggression, and parental history of alcoholism. Results of this study are contrasted with the adult psychiatric literature.
Metrics
Details
- Title
- Thyroid Stimulating Hormone Response to Thyrotropin in Prepubertal Depression
- Creators
- MANUEL R. Garcia - University of California—San DiegoNEAL D. Ryan - University of California, San DiegoHARRIS Rabinovitch - University of California, San DiegoPAUL Ambrosini - University of California San DiegoJAN Twomey - University of California, San DiegoSATTISH Iyengar - University of California, San DiegoHANA Novacenko - University of California, San DiegoBEVERLY Nelson - University of California, San DiegoJOAQUIM PUIG-ANTICH - University of California, San DiegoBrittany Nelson - Health Management and Policy
- Publication Details
- Journal of the American Academy of Child and Adolescent Psychiatry, v 30(3), pp 398-406
- Publisher
- Elsevier
- Grant note
- MH #40557 / National Institute of Mental Health Grant
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- [Retired Faculty]; Health Management and Policy
- Web of Science ID
- WOS:A1991FM31600008
- Scopus ID
- 2-s2.0-47649121561
- Other Identifier
- 991019184301304721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Pediatrics
- Psychiatry
- Psychology, Developmental