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Accepted (AM)Open Access (License Unspecified), Open
Journal article
Time-Dependent Processes in Stem Cell-Based Tissue Engineering of Articular Cartilage
Stem cell reviews, v 8(3), pp 863-881
2012
PMID: 22016073
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Articular cartilage (AC), situated in diarthrodial joints at the end of the long bones, is composed of a single cell type (chondrocytes) embedded in dense extracellular matrix comprised of collagens and proteoglycans. AC is avascular and alymphatic and is not innervated. At first glance, such a seemingly simple tissue appears to be an easy target for the rapidly developing field of tissue engineering. However, cartilage engineering has proven to be very challenging. We focus on time-dependent processes associated with the development of native cartilage starting from stem cells, and the modalities for utilizing these processes for tissue engineering of articular cartilage.
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Details
- Title
- Time-Dependent Processes in Stem Cell-Based Tissue Engineering of Articular Cartilage
- Creators
- Ivana Gadjanski - Columbia UniversityKara Spiller - Columbia UniversityGordana Vunjak-Novakovic - Columbia University
- Publication Details
- Stem cell reviews, v 8(3), pp 863-881
- Publisher
- Humana Press Inc
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000307333100021
- Scopus ID
- 2-s2.0-84865531619
- Other Identifier
- 991019176800204721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- International collaboration
- Web of Science research areas
- Cell & Tissue Engineering
- Cell Biology
- Medicine, Research & Experimental