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Titration Streptomycin Therapy for Bilateral Meniere's Disease: A Preliminary Report
Journal article   Peer reviewed

Titration Streptomycin Therapy for Bilateral Meniere's Disease: A Preliminary Report

Malcolm D. Graham, Robert T. Sataloff and John L. Kemink
Otolaryngology-head and neck surgery, v 92(4), pp 440-447
Aug 1984
PMID: 6435066

Abstract

Intramuscular dosages of streptomycin sulfate were titrated in eight patients with bilateral Meniere's disease in an attempt to alleviate disabling vertigo and hearing loss. It appears possible to eliminate the vertiginous episodes, preserve or improve hearing, and avoid ataxia and oscillopsia in most of these individuals. At present we consider this treatment regimen our first choice of therapy in people with bilateral active Meniere's disease or in patients whose only hearing ear is actively fluctuating and in whom associated disabling vertigo is present. Great caution and supervision should be exercised in the use of streptomycin titration therapy in the individual with bilateral Meniere's disease, as further experience is required to determine the efficacy of this form of management.

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39 citations in Scopus

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Collaboration types
Domestic collaboration
Web of Science research areas
Otorhinolaryngology
Surgery
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