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Tolerability of Six Months Indirect Cold (Physical) Plasma Treatment of the Scalp for Hair Loss
Journal article   Peer reviewed

Tolerability of Six Months Indirect Cold (Physical) Plasma Treatment of the Scalp for Hair Loss

Afshan Khan, Shilpa Malik, Jasmit Walia, Gregory Fridman, Alexander Fridman and Peter C. Friedman
Journal of drugs in dermatology, v 19(12), pp 1177-1180
01 Dec 2020
PMID: 33346510

Abstract

Dermatology Life Sciences & Biomedicine Science & Technology
Androgenetic alopecia (AGA) is a chronic form of hair loss. Cold atmospheric (physical) plasma (CAP) is partly ionized gas with various widely researched effects on living tissues. CAP is an emerging treatment modality in dermatology with uses for chronic leg ulcer, actinic keratosis, warts, and other applications. Its previously demonstrated ability to induce stem cell differentiation in various cell types makes CAP a possible treatment option for AGA. Directly creating CAP on the scalp surface has drawbacks, but indirect CAP treatment-when a CAP-treated liquid is used as topical therapy-offers an alternative. In a clinical pilot study, we treated 14 patients with AGA using the indirect CAP method for three months (4 patients) and six months (10 patients). The indirect CAP treatment was well tolerated and while the primary goal of the study was not to assess efficacy, most patients reported improvement, and the investigator's assessment also showed improvement in most patients. Our findings create the foundation for longer, extensive trials to systematically assess the efficacy of indirect CAP treatment for AGA.

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Dermatology
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