Logo image
New search Researchers Research units
Sign in
Toll-Like Receptor 2 and Its Relationship With Streptococcus in Psoriasis
Journal article   Peer reviewed

Toll-Like Receptor 2 and Its Relationship With Streptococcus in Psoriasis

Jing Zhang, Christine Shaver, Lane Neidig, Krister Jones, Carrie A Cusack and Herbert B Allen
Skinmed, v 15(1), pp 27-30
2017
PMID: 28270306

Abstract

Biomarkers - blood Female Humans Immunity, Innate - immunology Male Prognosis Psoriasis - etiology Psoriasis - microbiology Psoriasis - physiopathology Risk Assessment Staining and Labeling Streptococcal Infections - complications Streptococcal Infections - immunology Streptococcal Infections - physiopathology Streptococcus - immunology Streptococcus - pathogenicity Toll-Like Receptor 2 - metabolism
The authors present the immunopathologic findings of Toll-like receptor 2 in psoriasis. This novel work shows positive staining within the dermal capillaries in psoriatic lesions. Neither normal skin nor lesional skin in eczema showed similar staining. The authors postulate how the activation of this innate immune system reactant plays a significant role in psoriasis and show how it may be associated with a cascade of events that begins with streptococcus and ends with psoriasis.

Metrics

4 Record Views

Details

Logo image