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Top-Down Anticipatory Control in Prefrontal Cortex
Journal article   Peer reviewed

Top-Down Anticipatory Control in Prefrontal Cortex

Hualou Liang and Hongbin Wang
Theory in biosciences = Theorie in den Biowissenschaften, v 122(1), pp 70-86
2003

Abstract

Anticipation Conditioning Event-related potentia Synchronization Temporal Difference Learning
The prefrontal cortex has been implicated in a wide variety of executive functions, many involving some form of anticipatory attention. Anticipatory attention involves the pre-selection of specific sensory circuits to allow fast and efficient stimulus processing and a subsequently fast and accurate response. It is generally agreed that the prefrontal cortex plays a critical role in anticipatory attention by exerting a facilitatory “top-down” bias on sensory pathways. In this paper we review recent results indicating that synchronized activity in prefrontal cortex, during anticipation of visual stimulus, can predict features of early visual stimulus processing and behavioral response. Although the mechanisms involved in anticipatory attention are still largely unknown, we argue that the synchronized oscillation in prefrontal cortex is a plausible candidate during sustained visual anticipation. We further propose a learning hypothesis that explains how this top-down anticipatory control in prefrontal cortex is learned based on accumulated prior experience by adopting a Temporal Difference learning algorithm.

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Web of Science research areas
Biology
Mathematical & Computational Biology
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