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Topical micronutrients in atopic dermatitis-An evidence-based review
Journal article   Open access   Peer reviewed

Topical micronutrients in atopic dermatitis-An evidence-based review

M Maarouf, A R Vaughn and V Y Shi
Dermatologic therapy, v 31(5), pp e12659-n/a
Sep 2018
DOI: https://doi.org/10.1111/dth.12659
PMID: 30019437
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://doi.org/10.1111/dth.12659View
Published, Version of Record (VoR)Open Access (License Unspecified),  Open

Abstract

Administration, Cutaneous Ascorbic Acid - therapeutic use Dermatitis, Atopic - drug therapy Evidence-Based Medicine Humans Magnesium - therapeutic use Manganese - therapeutic use Trace Elements - administration & dosage Trace Elements - therapeutic use Vitamin A - therapeutic use Vitamin B Complex - therapeutic use Vitamin D - therapeutic use Vitamin E - therapeutic use Vitamins - administration & dosage Vitamins - therapeutic use Zinc - therapeutic use
The role of dietary factors is an important and controversial topic in the pathogenesis of atopic dermatitis (AD). Despite the preponderance of consumer products utilizing oral micronutrients supplementation for relief AD symptoms, less attention has been paid on the utility of topical micronutrients, specifically for individuals with AD. We review evidence on topical formulations of vitamins (A, B, C, D, and E) and trace minerals (magnesium, manganese, zinc, and iodine) for treatment of AD. While topical B, C, and E formulations appear to provide some benefit to AD individuals, topical vitamin A has no utility, and topical vitamin D may exacerbate symptoms. Magnesium, zinc, and iodine all appear to improve AD through anti-inflammatory and anti-microbial effects, though future studies must evaluate their use as monotherapy. The exposition of the effects that topical micronutrients have on AD offers an adjuvant treatment modality for this common inflammatory dermatosis.

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5 Record Views
21 citations in Web of Science
20 citations in Scopus

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UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

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Collaboration types
Domestic collaboration
Web of Science research areas
Dermatology
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