Journal article
Transient fluctuations in cognitive functioning in schizophrenia based on single-case study methods
Schizophrenia research, v 17(2), pp 201-209
1995
PMID: 8562495
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The stability of cognitive performance in four schizophrenia patients was examined over a short time period. A cognitive battery highly sensitive to organismic state (the Repeatable Cognitive-Perceptual-Motor Battery, RCPM) was utilized. Single-case statistical methods tested for within-individual change across five assessments at two week intervals. All four subjects showed statistically significant post-baseline variation in a global measure of impairment (average impairment rating score) and in at least 50% of the individual tests having adequate test-retest reliability. Data are interpreted as providing suggestive evidence of transient fluctuations in performance within a stable window of impaired cognitive functioning. These fluctuations appear substantial enough to influence both research and clinical outcomes. The benefits of the single-case methodology employed are discussed. The data suggest that significant transient fluctuations in cognitive performance can be observed in schizophrenia in domains purported to represent vulnerability markers of the disorder. The importance of accounting for these transient fluctuations in the attempt to identify enduring, trait-like characteristics of cognitive functioning in schizophrenia is discussed.
Metrics
Details
- Title
- Transient fluctuations in cognitive functioning in schizophrenia based on single-case study methods
- Creators
- Joseph I. Tracy - York College of PennsylvaniaRebecca Oesterling - York College of PennsylvaniaRichard C. Josiassen - York College of Pennsylvania
- Publication Details
- Schizophrenia research, v 17(2), pp 201-209
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Psychiatry
- Web of Science ID
- WOS:A1995TE00200009
- Scopus ID
- 2-s2.0-0028832810
- Other Identifier
- 991019183967104721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Psychiatry