Journal article
Transoral surgery vs intensity-modulated radiotherapy for early supraglottic cancer: a systematic review
Current opinion in otolaryngology & head and neck surgery, v 25(2), pp 133-141
01 Apr 2017
PMID: 28106658
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Purpose of review
To provide clinicians with a critical review of outcomes for endolaryngeal surgery and intensity-modulated radiation therapy (IMRT) for early-stage supraglottic cancer.
Recent findings
A total of 971 potential articles were reviewed, with inclusion of 14 studies comparing IMRT with transoral surgery. One study analyzed IMRT, one transoral robotic surgery, and the remaining were transoral laser microsurgery studies. A weighted average and 95% confidence interval of all surgery patients showed a local control of 90.36 +/- 1.14% (n = 118) for T1 lesions, 83.09 +/- 1.36% (n = 232) for T2 lesions, and 86.38 +/- 0.82% (n = 429) overall. The one study examining IMRT outcomes reported a local control of 70 +/- 10.07% and overall survival of 63% over 5 years for T2 lesions (n = 78), with no reported T1 data or secondary outcomes.
Summary
Endolaryngeal surgery as definitive therapy for T1 and T2 supraglottic cancer has excellent local control. Although endolaryngeal surgery performed better than IMRT, the data are limited, and a definitive comparison with surgery cannot be made. Additional studies are required.
Metrics
Details
- Title
- Transoral surgery vs intensity-modulated radiotherapy for early supraglottic cancer: a systematic review
- Creators
- Mark S. Swanson - Univ Southern Calif, Dept Otolaryngol Head & Neck Surg, 1540 Alcazar St,Suite 204 M, Los Angeles, CA 90033 USAGarren Low - College Station Medical CenterUttam K. Sinha - Univ Southern Calif, Dept Otolaryngol Head & Neck Surg, 1540 Alcazar St,Suite 204 M, Los Angeles, CA 90033 USANiels Kokot - Univ Southern Calif, Dept Otolaryngol Head & Neck Surg, 1540 Alcazar St,Suite 204 M, Los Angeles, CA 90033 USA
- Publication Details
- Current opinion in otolaryngology & head and neck surgery, v 25(2), pp 133-141
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 9
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Otolaryngology (and Head and Neck Surgery)
- Web of Science ID
- WOS:000397990300007
- Scopus ID
- 2-s2.0-85009945342
- Other Identifier
- 991022008191004721
UN Sustainable Development Goals (SDGs)
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Otorhinolaryngology