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Published, Version of Record (VoR)CC BY-NC V4.0, Open
Journal article
Transplanting Cells for Spinal Cord Repair: Who, What, When, Where and Why?
Cell transplantation, v 28(4), pp 388-399
01 Apr 2019
PMID: 30654638
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Cellular transplantation for repair of the injured spinal cord has a rich history with strategies focused on neuroprotection, immunomodulation, and neural reconstruction. The goal of the present review is to provide a concise overview and discussion of five key themes that have become important considerations for rebuilding functional neural networks. The questions raised include: (i) who are the donor cells selected for transplantation, (ii) what is the intended target for repair, (iii) when is the optimal time for transplantation, (iv) where should the cells be delivered, and lastly (v) why does cell transplantation remain an attractive candidate for promoting neural repair after injury? Recent developments in neurobiology and engineering now enable us to start addressing these questions with multidisciplinary expertise and methods.
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Details
- Title
- Transplanting Cells for Spinal Cord Repair: Who, What, When, Where and Why?
- Creators
- Lyandysha V. Zholudeva - Drexel UniversityMichael A. Lane - Drexel University
- Publication Details
- Cell transplantation, v 28(4), pp 388-399
- Publisher
- Sage
- Number of pages
- 12
- Grant note
- R01 NS081112; RO1 NS104291 / NINDS, NIH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS) P01NS055976 / NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS) Spinal Cord Research Center at Drexel University, College of Medicine Moseley Foundation Drexel Deans Fellowship for Collaborative or Themed Research
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Neurobiology and Anatomy
- Web of Science ID
- WOS:000476672400004
- Scopus ID
- 2-s2.0-85068916517
- Other Identifier
- 991019169326604721
UN Sustainable Development Goals (SDGs)
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Cell & Tissue Engineering
- Medicine, Research & Experimental
- Transplantation