Journal article
Treat to Target, Remission and Low Disease Activity in the Treatment of Rheumatoid Arthritis
Current treatment options in rheumatology, v 6(3), pp 260-267
01 Sep 2020
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Purpose of this reviewTreat to Target (T2T) and disease activity measurements have changed the way rheumatologists treat patients, particularly those with rheumatoid arthritis. The author will address the history behind the development of T2T as well as some practical aspects around the use of T2T and disease activity measurement.Recent findingsThe stated targets for disease activity are remission and low disease activity (LDA). However, given that these are "surrogate" measures, each individual measure may, in fact, be measuring a different level of disease activity. Ultimately, no single measure is better than any other. Despite this, recent work has demonstrated that patients in whom the target can be attained, there are better outcomes. How long to wait before making a change in therapy and how deep to push toward the absolute abrogation of disease remains unclear.SummaryTreat to Target is an attainable and acceptable goal for treating patients with rheumatoid arthritis. The deeper the response, the better the outcome, but a low level of disease activity may be acceptable. Treating patients to target will require that patients are evaluated, using a metric, and that changes are made in therapies, based on this metric and sound medical judgement.
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Details
- Title
- Treat to Target, Remission and Low Disease Activity in the Treatment of Rheumatoid Arthritis
- Creators
- Martin Jan Bergman - Drexel University
- Publication Details
- Current treatment options in rheumatology, v 6(3), pp 260-267
- Publisher
- Springer Nature
- Number of pages
- 8
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Medicine (Graduate)
- Web of Science ID
- WOS:000657176300009
- Other Identifier
- 991019169800304721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Rheumatology