Journal article
Treatment of Neuropathic Pain and Functional Limitations Associated With Multiple Sclerosis Using an MRI-Compatible Spinal Cord Stimulator: A Case Report With Two Year Follow-Up and Literature Review
Neuromodulation (Malden, Mass.), v 19(4), pp 406-412
01 Jun 2016
PMID: 27019220
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Objective: To report a case with two years follow-up of neuropathic pain and functional limitations associated with multiple sclerosis (MS) effectively treated with an MRI conditional spinal cord stimulator (SCS) system that allowed for spinal imaging. To present a comprehensive literature review of spinal cord stimulator utilization in the treatment of multiple sclerosis.
Design: Case report and literature review.
Intervention: Treatment was a spinal cord stimulation implant after successful trial. Pain scores, medication utilization, and functional outcomes were reviewed. Pre-and post-SCS implant MRI spine images were obtained.
Results: At 24 months follow-up, the patient has had a 77% reduction in pain and a 99% reduction in opioid use. Furthermore, he had improvement in reported tactile sensation, spasticity levels, and ambulation. Post-SCS implant, MRI images at 18 months follow-up provided the ability to review the spinal cord with minimal artifact. No new MS documented plaques occurred during this time period. A literature review demonstrated 33 published reports including a total of 496 trialed and 744 implanted patients. Only 3 of the reports occurred after the year 2000.
Conclusions: We report the successful treatment of MS-associated pain and functional limitations with an MRI conditional spinal cord stimulator system. The ability to obtain post-implant MRI imaging of not only the brain but also the spinal cord in MS patients allows for the continued need to document and follow disease progression, especially with the advancements in pharmacological therapy.
Metrics
Details
- Title
- Treatment of Neuropathic Pain and Functional Limitations Associated With Multiple Sclerosis Using an MRI-Compatible Spinal Cord Stimulator: A Case Report With Two Year Follow-Up and Literature Review
- Creators
- David A. Provenzano - Pain Diagnostics and Interventional Care, Sewickley, PA, USA.Joseph R. Williams - Pain Diagnostics and Interventional Care, Sewickley, PA, USA.Gaye Jarzabek - Pain Diagnostics and Interventional Care, Sewickley, PA, USA.Leonard A. DeRiggi - Sewickley Valley HospitalThomas F. Scott - Allegheny General Hospital
- Publication Details
- Neuromodulation (Malden, Mass.), v 19(4), pp 406-412
- Publisher
- Wiley
- Number of pages
- 7
- Grant note
- Biogen-Idec; Biogen Novartis Teve Neuroscience Genzyme; Sanofi-Aventis; Genzyme Corporation
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Neurology
- Web of Science ID
- WOS:000380898300013
- Scopus ID
- 2-s2.0-84976295609
- Other Identifier
- 991019167327404721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Clinical Neurology
- Medicine, Research & Experimental
- Neurosciences