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Trends in HPLC - Wide pH-range columns and capillary columns
Journal article   Open access   Peer reviewed

Trends in HPLC - Wide pH-range columns and capillary columns

B E Boyes, A Gratzfeld-Husgen and R Weber
Chimia, v 55(1-2), pp 48-49
01 Jan 2001
url
https://doi.org/10.2533/chimia.2001.48View
Published, Version of Record (VoR)CC BY-NC V4.0 Open

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
The topic covers the current trends in HPLC column development to robust columns that extend the usable pH-range. Examples are given an how intelligent surface chemistry enables silica-based materials to be used in the pH-range 1 to 11. The resulting packing materials combine the extreme mechanically stability of silica with an excellent chemical stability. Especially in the LC-MS community high pH-applications are becoming more popular, because of the problems that ion-pair reagents cause with this detection technique. The life-science arena with small sample amounts demands smaller id columns i.e. capillary columns. Capillary-HPLC instruments are now commercially available and the presentation will shed some light on various capillary column applications.

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Collaboration types
Industry collaboration
Domestic collaboration
Web of Science research areas
Chemistry, Multidisciplinary
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