Journal article
Triple sugar screen breath hydrogen test for sugar intolerance in children with functional abdominal symptoms
Indian journal of gastroenterology, v 29(5), pp 196-200
Sep 2010
PMID: 20978880
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Sugar intolerance and functional gastrointestinal disorders are both common in school age children. Both may present with similar complaints such as abdominal pain, diarrhea and bloating. Lactose, fructose and sucrose hydrogen breath tests are widely used to detect sugar malabsorption.
To determine the proportion of children with symptoms of functional gastrointestinal disorders (FGID) that have sugar intolerance as determined by using a breath hydrogen test.
We prospectively enrolled subjects with chronic abdominal pain, bloating and/or chronic diarrhea. All subjects underwent triple sugar screen hydrogen breath test (TSST) using the combined sugar solution. Breath hydrogen concentration ≥ 20 ppm above baseline was interpreted a positive test for sugar malabsorption.
A positive hydrogen breath test consistent with sugar malabsorption was found in 5 out of 31 (16%) subjects. Three of these subjects were confirmed to have lactose malabsorption based on small bowel lactase enzyme analysis or subsequent lactose hydrogen breath test. One subject with positive TSST was diagnosed with fructose malabsorption based on dietary history; he improved on a limited fructose diet, and one was diagnosed to have gastric Crohn's disease.
Approximately one in six children with symptoms of FGID had sugar intolerance as determined by the TSST.
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Details
- Title
- Triple sugar screen breath hydrogen test for sugar intolerance in children with functional abdominal symptoms
- Creators
- Jonathan E Teitelbaum - Drexel UniversityDolly Ubhrani - Monmouth Medical Center
- Publication Details
- Indian journal of gastroenterology, v 29(5), pp 196-200
- Publisher
- Springer Nature
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pediatrics
- Web of Science ID
- WOS:000210590200006
- Scopus ID
- 2-s2.0-79952468441
- Other Identifier
- 991019168310304721
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Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Gastroenterology & Hepatology