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Journal article
Tropicamide (1%) : An effective cycloplegic agent for myopic children
Investigative ophthalmology & visual science, v 42(8), pp 1728-1735
Jul 2001
PMID: 11431435
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
PURPOSE. To evaluate the cycloplegic effect of 1% tropicamide in myopic children and to determine whether its efficacy is associated with age, gender, iris color, ethnicity, magnitude of the refractive error, or latent error.
METHODS. Four hundred sixty-nine children enrolled in the Correction of Myopia Evaluation Trial (COMET; a multicenter, randomized, double-masked clinical trial evaluating the rate of progression of juvenile-onset myopia in children wearing progressive-addition versus single-vision lenses) were given I drop of proparacaine in each eye followed 1 minute later by 1 drop of 1% tropicamide and then a second drop of 1% tropicamide 4 to 6 minutes later. Five accommodative responses to 20/100 letters located at 4 m and 33 cm were obtained in each eye with an autorefractor, 20 minutes after the second drop. Residual accommodation was calculated as the difference between the mean spherical equivalent responses obtained at the two distances. An examiner graded iris color, and ethnicity was reported by the children's parents or guardians.
RESULTS. The mean residual accommodation was small: 0.38 +/- 0.41 diopters (D) in the right eye and 0.30 +/- 0.41 D in the left eye. Small but statistically significant differences in residual accommodation were associated with ethnicity, but not with any of the other factors.
CONCLUSIONS. Tropicamide (1%) is an effective cycloplegic agent in myopic children.
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Details
- Title
- Tropicamide (1%) : An effective cycloplegic agent for myopic children
- Creators
- Ruth E. Manny - University of HoustonMohamed Hussein - Stony Brook UniversityMitchell M Scheiman - Drexel University, Pennsylvania College of Optometry at Salus University (2008-2025)Daniel Kurtz - New England College of OptometryKathy Niemann - University of AlabamaKathleen Zinzer - Salus University
- Publication Details
- Investigative ophthalmology & visual science, v 42(8), pp 1728-1735
- Publisher
- ASSOC RESEARCH VISION OPHTHALMOLOGY INC
- Number of pages
- 8
- Grant note
- NEI NIH HHS: EY11740, EY11805, EY11752, EY11754, EY11756, EY11755
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pennsylvania College of Optometry (PCO)
- Web of Science ID
- WOS:000169798500011
- Scopus ID
- 2-s2.0-0034943573
- Other Identifier
- 991021900815004721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Ophthalmology