Two‐Year Results of Think Health! ¡Vive Saludable!: A Primary Care Weight‐Management Trial
Shiriki K. Kumanyika, Knashawn H. Morales, Kelly C. Allison, A. Russell Localio, David B. Sarwer, Etienne Phipps, Jennifer E. Fassbender, Adam G. Tsai and Thomas A. Wadden
Obesity (Silver Spring, Md.), v 26(9), pp 1412-1421
Objective
Think Health! ¡Vive Saludable! evaluated a moderate‐intensity, lifestyle behavior‐change weight‐loss program in primary care over 2 years of treatment. Final analyses examined weight‐change trajectories by treatment group and attendance.
Methods
Adult primary care patients (n = 261; 84% female; 65% black; 16% Hispanic) were randomly assigned to Basic Plus (moderate intensity; counseling by primary care clinician and a lifestyle coach) or Basic (clinician counseling only). Intention‐to‐treat analyses used all available weight measurements from data collection, treatment, and routine clinical visits. Linear mixed‐effects regression models adjusted for treatment site, gender, and age, and sensitivity analyses evaluated treatment attendance and the impact of loss to follow‐up.
Results
Model‐based estimates for 24‐month mean (95% CI) weight change from baseline were −1.34 kg (−2.92 to 0.24) in Basic Plus and −1.16 kg (−2.70 to 0.37) in Basic (net difference −0.18 kg [−2.38 to 2.03]; P = 0.874). Larger initial weight loss in Basic Plus was attenuated by a ~0.5‐kg rebound at 12 to 16 months. Each additional coaching visit was associated with a 0.37‐kg greater estimated 24‐month weight loss (P = 0.01).
Conclusions
These findings in mostly black and Hispanic female primary care patients suggest that strategies to improve treatment attendance may improve weight loss resulting from moderate‐intensity counseling.
Two‐Year Results of Think Health! ¡Vive Saludable!: A Primary Care Weight‐Management Trial
Creators
Shiriki K. Kumanyika - University of Pennsylvania
Knashawn H. Morales - University of Pennsylvania
Kelly C. Allison - University of Pennsylvania
A. Russell Localio - University of Pennsylvania Perelman School of Medicine
David B. Sarwer - Temple University
Etienne Phipps - Einstein Healthcare Network
Jennifer E. Fassbender - University of Pennsylvania
Adam G. Tsai - University of Pennsylvania
Thomas A. Wadden - University of Pennsylvania
Publication Details
Obesity (Silver Spring, Md.), v 26(9), pp 1412-1421
Publisher
Wiley
Number of pages
10
Grant note
Pennsylvania Department of Health (K12-HD043459-04)
NIH National Institute of Diabetes and Digestive and Kidney Diseases (R21DK089422)
NIH National Institute of Mental Health (K01MH073903)
NIH National Institute of Child Health and Human Development (K12‐HD043459‐04)
Resource Type
Journal article
Language
English
Academic Unit
Urban Health Collaborative; Dana and David Dornsife School of Public Health
Web of Science ID
WOS:000444803000007
Scopus ID
2-s2.0-85052817622
Other Identifier
991019312432904721
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