Journal article
Type I Kounis syndrome variant: A case report and literature review
Avicenna journal of medicine, v 8(1), pp 37-39
Jan 2018
PMID: 29404272
Abstract
Abstract
Kounis syndrome defined as the occurrence of acute coronary syndrome in the setting of allergic reaction due to mast cells activation and inflammatory mediators release that induces coronary vasospasm, plaque erosion, or even stent thrombosis. A 25-year-old postpartum female with asthma and recurrent episodes of chest pain was admitted with ST-segment elevation myocardial infarction in the setting of coronary artery spasms. The patient was started on calcium channel blockers and nitrite-based medication with no improvement. She was noted to have eosinophilia and initiation of corticosteroid-based regimen lead to resolution of chest pain episodes and normalization of eosinophilia. Kounis syndrome should be considered in young patients with chest pain. Coronary vasodilators are considered as the first-line of treatment. The use of corticosteroids has been described in the literature in severe or refractory cases.
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Details
- Title
- Type I Kounis syndrome variant: A case report and literature review
- Creators
- Abdullah Haddad - Allegheny General HospitalTriston Smith - Allegheny General HospitalAneel Bole - Allegheny General HospitalMoneal Shah - Allegheny General HospitalMithun Chakravarthy - Allegheny General Hospital
- Publication Details
- Avicenna journal of medicine, v 8(1), pp 37-39
- Publisher
- Thieme
- Number of pages
- 3
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- General Internal Medicine
- Other Identifier
- 991022053780504721