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Ultrasensitive Detection of Cu2+ Using a Microcantilever Sensor Modified with L-Cysteine Self-Assembled Monolayer
Journal article   Peer reviewed

Ultrasensitive Detection of Cu2+ Using a Microcantilever Sensor Modified with L-Cysteine Self-Assembled Monolayer

Xiaohe Xu, Na Zhang, Gilbert M. Brown, Thomas G. Thundat and Hai-Feng Ji
Applied biochemistry and biotechnology, v 183(2), pp 555-565
01 Oct 2017
PMID: 28540518

Abstract

Biochemistry & Molecular Biology Biotechnology & Applied Microbiology Life Sciences & Biomedicine Science & Technology
A microcantilever was modified with a self-assembled monolayer (SAM) of L-cysteine for the sensitively and selectively response to Cu(II) ions in aqueous solution. The microcantilever undergoes bending due to sorption of Cu(II) ions. The interaction of Cu(II) ions with the L-cysteine on the cantilever is diffusion controlled and does not follow a simple Langmuir adsorption model. A concentration of 10(-10) M Cu(II) was detected in a fluid cell using this technology. Other cations, such as Ni2+, Zn2+, Pb2+, Cd2+, Ca2+, K+, and Na+, did not respond with a significant deflection, indicating that this L-cysteine-modified cantilever responded selectively and sensitively to Cu(II).

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Collaboration types
Domestic collaboration
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Web of Science research areas
Biochemistry & Molecular Biology
Biotechnology & Applied Microbiology
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