Journal article
Ultrasonic tissue characterization of experimental venous intimal hyperplasia
Ultrasound in medicine & biology, v 19(4), pp 299-308
1993
PMID: 8346604
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Ultrasonic tissue characterization (UTC) employing slope and Y-intercept parameters from the normalized power spectrum of backscattered echoes was employed in vivo to study compositional changes in the walls of pig jugular veins in which thrombi were experimentally induced. Light microscopy revealed these changes to be intimal hyperplasia with an early predominance of smooth muscle cells and a later mixture of smooth muscle cells and collagen deposits. UTC distinguished intimal hyperplasia from previously reported data from luminal throm-bosis UTC. Furthermore, UTC was able to discriminate between early (predominantly smooth muscle cells) and older (smooth muscle cells plus collagen deposits) intimal hyperplasia. The study suggests that intimal hyperplasia in the experimental model used may be organized thrombus and that UTC may be able to follow both the development of wall changes as well as luminal changes occurring in venous thrombosis.
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Details
- Title
- Ultrasonic tissue characterization of experimental venous intimal hyperplasia
- Creators
- Richard E. Parsons - Drexel UniversityBernard Sigel - Drexel UniversityErnest J. Feleppa - Riverside Research InstituteRobert M. Golub - Drexel UniversityJeffery Justin - Drexel UniversityVanlila K. Swami - Drexel UniversityMary Rorke - Riverside Research InstituteAndrew Kalisz - Riverside Research InstituteCharles D. Long - Drexel UniversityAdil Can - Drexel UniversityFrederic L. Lizzi - Riverside Research InstituteHiroshi Kitamura - Drexel University
- Publication Details
- Ultrasound in medicine & biology, v 19(4), pp 299-308
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- [Retired Faculty]
- Web of Science ID
- WOS:A1993LE48600005
- Scopus ID
- 2-s2.0-0027310230
- Other Identifier
- 991019183977304721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Acoustics
- Radiology, Nuclear Medicine & Medical Imaging