Journal article
Ultraviolet A1 phototherapy for improvement of hand function in scleroderma: a blinded prospective study
British journal of dermatology (1951), v 194(4), pp 789-791
19 Mar 2026
PMID: 41340253
Abstract
Effective tools for improving sclerotic hand changes in patients with systemic sclerosis are lacking; thus, we conducted a single-blind prospective randomized clinical trial investigating the impact of UVA1 phototherapy on scleroderma of the hands. Seven patients were unilaterally treated, and we found no evidence of significant change in Hand Mobility in Scleroderma (HAMIS) scores after 30 treatments. However, patients did report significant health-related outcome changes in the emotional, symptomatic and functional domains of Skindex-16 [beta = -34.1 (95% CI -47.0 to -21.3), -26.3 (-38.1 to -14.4) and -13.1 (-20.9 to -5.41), respectively].
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Details
- Title
- Ultraviolet A1 phototherapy for improvement of hand function in scleroderma: a blinded prospective study
- Creators
- Rachel M. Seifert - University of UtahChristiaan H. Noot - University of UtahVikram N. Sahni - Drexel University, DermatologyAmber Jimenez - University of UtahLaurel Gray - University of UtahZachary H. Hopkins - University of UtahTracy M. Frech - Vanderbilt University Medical CenterChristopher B. Hansen - University of Utah
- Publication Details
- British journal of dermatology (1951), v 194(4), pp 789-791
- Publisher
- Oxford Univ Press
- Number of pages
- 3
- Grant note
- Skaggs Foundation
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Dermatology
- Web of Science ID
- WOS:001656367100001
- Scopus ID
- 2-s2.0-105033855181
- Other Identifier
- 991022180002904721