Logo image
Unicystic ameloblastoma: A retrospective study on recurrent factors from a single institute database
Journal article   Open access   Peer reviewed

Unicystic ameloblastoma: A retrospective study on recurrent factors from a single institute database

Rong Yang, Xiaohu Lin, Wenming Zhang, Sandhya Gokavarapu, Chengzhong Lin, Zhenhu Ren, Yongjie Hu, Wei Cao and Tong Ji
Oral diseases, v 30(3), pp 1475-1482
01 Apr 2024
PMID: 36564985
url
https://doi.org/10.1111/odi.14477View
Published, Version of Record (VoR) Restricted

Abstract

Dentistry, Oral Surgery & Medicine Life Sciences & Biomedicine Science & Technology
Objective: Unicystic ameloblastomas are a variant of ameloblastoma with a definite recurrence rate because of the biological behaviours of the tumour. The risk factors associated with disease recurrence were analysed in this retrospective study.Methods: A total of 132 patients with primary unicystic ameloblastoma reported in a tertiary hospital from 2005 to 2015 were analysed to identify the clinic-pathological and radiological factors associated with recurrence using univariate and multivariate Cox regression analyses.Results: The mean volume was 30.54cm3 +/- 12.55 cm3, and this value differed significantly according to recurrence (p < 0.001). Root resorption and bone cortex/soft tissue invasion were also significantly associated with recurrence among unicystic ameloblastoma patients (p = 0.017 vs. p < 0.001, respectively). A new stage classifica- tion system was developed to predict disease recurrence of patients. The multivariate Cox regression analysis revealed that the new stage classification system was the only predictor of disease recurrence in unicystic ameloblastoma patients (p < 0.001), regardless of root resorption, position and site characteristics.Conclusions: Volume, root resorption and bone cortex/soft tissue invasion were risk factors for disease recurrence among unicystic ameloblastoma patients. The new stage classification was an independent predictor of disease recurrence in patients with unicystic ameloblastoma.

Metrics

7 Record Views
6 citations in Scopus

Details

UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

Source: SDGs in the Output

InCites Highlights

Data related to this publication, from InCites Benchmarking & Analytics tool:

Web of Science research areas
Dentistry, Oral Surgery & Medicine
Logo image