Journal article
Unraveling Moyamoya Disease: A Systematic Review of Pathophysiology, Diagnosis, and Treatment
African Journal of Biomedical Research, v 28(3S), pp 205-216
2025
Abstract
Moyamoya disease (MMD) is a rare and chronic cerebrovascular disease characterized by progressive stenosis or occlusion of the blood vessels within the terminal intracranial aspect of the internal carotid artery and the circle of Willis, leading to the compensatory development of a fragile collateral vessel network at the base of the brain. These vascular features are responsible for the recurrent ischemic and/or hemorrhagic strokes seen in affected patients. Numerous studies have attempted to clarify the clinical features of Moyamoya, including its etiopathology and interventions. In recent years, the development of neuroimaging and surgical techniques has enhanced the understanding of MMD in patients. The purpose of this review is to discuss the hypothesized etiopathogenesis, clinical manifestations, and the current possible treatment options available for Moyamoya disease.
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Details
- Title
- Unraveling Moyamoya Disease: A Systematic Review of Pathophysiology, Diagnosis, and Treatment
- Creators
- Ganesh Chilukuri - Drexel UniversityAmba Viswanathan - Drexel UniversityAmy Job - Drexel UniversityVivek Joshi - Drexel University
- Publication Details
- African Journal of Biomedical Research, v 28(3S), pp 205-216
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Biochemistry and Molecular Biology
- Other Identifier
- 991022052805804721