Logo image
Unusual Case of Severe Lactic Acidosis in a Liver Transplant Patient
Journal article   Open access   Peer reviewed

Unusual Case of Severe Lactic Acidosis in a Liver Transplant Patient

Shweta Yemul Golhar, Michael S. Green and Stephen Guy
Case reports in transplantation, v 2017, pp 1-4
01 Jan 2017
PMID: 29391965
url
https://doi.org/10.1155/2017/3704309View
Published, Version of Record (VoR) Open

Abstract

Lactic acidosis is a standard indicator for oxygen debt and some other very significant causes. We describe a case of liver transplant patient presenting with vague abdominal pain and lactic acidosis without any liver dysfunction/failure/ischemia/rejection or sepsis. The imaging studies showed vague bowel edema and normal hepatic perfusion. The patient continued to deteriorate with rising lactic acidosis when a repeat CT abdomen eventually showed signs of lymphomatosis peritonei. Biopsy revealed the unusual diagnosis of posttransplant lymphoproliferative disorder. Immediate discontinuation of immunosuppression and initiation of chemotherapy led to clinical improvement. Our intention of presenting this case is to increase awareness of posttransplant lymphoma and propose lactic acidosis as not only an indicator of liver dysfunction or rejection but also an aid for diagnosis of this unusual but fatal and potentially curable condition.

Metrics

10 Record Views

Details

Logo image