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Unusual case of recurrent SMART (stroke-like migraine attacks after radiation therapy) syndrome
Journal article   Open access   Peer reviewed

Unusual case of recurrent SMART (stroke-like migraine attacks after radiation therapy) syndrome

Ramnath Santosh Ramanathan, Gayathri Sreedher, Konark Malhotra, Zain Guduru, Deeksha Agarwal, Mary Flaherty, Timothy Leichliter and Sandeep Rana
Annals of the Indian Academy of Neurology, v 19(3), pp 399-401
01 Jul 2016
PMID: 27570398
url
https://doi.org/10.4103/0972-2327.168634View
Published, Version of Record (VoR)Open Access (License Unspecified) Open

Abstract

Case Report
Stroke-like migraine attacks after radiation therapy (SMART) syndrome is a rare delayed complication of cerebral radiation therapy. A 53-year-old female initially presented with headache, confusion and left homonymous hemianopia. Her medical history was notable for cerebellar hemangioblastoma, which was treated with radiation in 1987. Her initial brain MRI (magnetic resonance imaging) revealed cortical enhancement in the right temporo-parieto-occipital region. She improved spontaneously in 2 weeks and follow-up scan at 4 weeks revealed no residual enhancement or encephalomalacia. She presented 6 weeks later with aphasia. Her MRI brain revealed similar contrast-enhancing cortical lesion but on the left side. Repeat CSF studies was again negative other than elevated protein. She was treated conservatively and recovered completely within a week. Before diagnosing SMART syndrome, it is important to rule out tumor recurrence, encephalitis, posterior reversible encephalopathy syndrome (PRES) and stroke. Typically the condition is self-limiting, and gradually resolves.

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Collaboration types
Domestic collaboration
Web of Science research areas
Clinical Neurology
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