Files and links (1)
Published, Version of Record (VoR)Open Access (License Unspecified), Open
Journal article
Uropathogenic Escherichia coli virulence and innate immune responses during urinary tract infection
Current opinion in microbiology, v 16(1), pp 100-107
01 Feb 2013
PMID: 23403118
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Urinary tract infections (UTI) are among the most common infectious diseases of humans and are the most common nosocomial infections in the developed world. It is estimated that 40-50% of women and 5% of men will develop a UTI in their lifetime, and UTI accounts for more than 1 million hospitalizations and $1.6 billion in medical expenses each year in the USA. Uropathogenic Escherichia coli (UPEC) is the primary cause of UTI. This review presents an overview of recent discoveries related to the primary virulence factors of UPEC and major innate immune responses to infection of the lower urinary tract. New and emerging themes in UPEC research are discussed in the context of the interface between host and pathogen.
Metrics
Details
- Title
- Uropathogenic Escherichia coli virulence and innate immune responses during urinary tract infection
- Creators
- Glen C. Ulett - Griffith UniversityMakrina Totsika - The University of QueenslandKolja Schaale - The University of QueenslandAlison J. Carey - Griffith UniversityMatthew J. Sweet - The University of QueenslandMark A. Schembri - The University of Queensland
- Publication Details
- Current opinion in microbiology, v 16(1), pp 100-107
- Publisher
- Current Biology Ltd
- Number of pages
- 8
- Grant note
- APP1005315 / National Health and Medical Research Council (NHMRC) of Australia NHMRC Senior Research Fellowship; National Health and Medical Research Council (NHMRC) of Australia FT110101048; FT100100657; FT100100662; DE130101169 / Australian Research Council APP1052464 / NHMRC Peter Doherty Australian Biomedical Fellowship; National Health and Medical Research Council (NHMRC) of Australia
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pediatrics; College of Medicine; Drexel University
- Web of Science ID
- WOS:000318056200016
- Scopus ID
- 2-s2.0-84875812043
- Other Identifier
- 991020099050904721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Microbiology