Background and Objectives Falls and fall-related injuries are significant public health issues for older adults, especially those with mild cognitive impairment (MCI). This study examined how an Artificial Intelligence (AI)-enabled assessment using in-home sensor-derived changes in functional mobility and gait compares to performance-based clinical assessment in older adults with and without MCI.Research Design and Methods We conducted a longitudinal, single-cohort observational study, recruiting 75 community-dwelling older adults residing in retirement and senior living communities (eligible if aged 65+ and able to walk household distances). Participants were assessed for MCI. A depth sensor, installed in each participant's residence, recorded in-home movement as silhouette depth images over a one-year period. AI/machine learning algorithms automatically identified, segmented, and analyzed walking segments to extract gait speed, stride time, stride length, and height of the individual walking. Timed Up and Go (TUG) score, gait speed, stride length, and stride time were captured continuously by the AI system and by a clinical expert at baseline, 3, 6, 9, and 12 months.Results The correlation between AI-based and performance-based TUG was strong and positive (r = 0.611, 95% CI: 0.354, 0.782). A moderate positive correlation between stride time and clinically assessed TUG was observed (r = 0.424, 95% CI: 0.193, 0.639).Discussion and Implications This study demonstrates that AI-enabled in-home monitoring can capture clinically meaningful indicators of functional mobility among older adults with and without MCI. As slowed gait speed and altered stride variability precede cognitive decline and heightened fall risk, a continuous in-home assessment can facilitate proactive interventions.
Journal article
Use of artificial intelligence to assess gait parameters in older adults with and without mild cognitive impairment
Innovation in aging, v 10(10), pigag082
14 Jul 2026
PMID: 42713607
Abstract
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Details
- Title
- Use of artificial intelligence to assess gait parameters in older adults with and without mild cognitive impairment
- Creators
- George Demiris - University of PennsylvaniaLiming Huang - University of PennsylvaniaSean L Harrison - University of PennsylvaniaMarjorie Skubic - University of MissouriJustine S Sefcik - Drexel UniversityTherese S Richmond - University of PennsylvaniaNancy Hodgson - University of Pennsylvania
- Publication Details
- Innovation in aging, v 10(10), pigag082
- Publisher
- Oxford University Press
- Number of pages
- 11
- Grant note
- National Institutes of Health: R01AG090377 Centers for Disease Control: R49CE003083
This work was supported in part by the Centers for Disease Control (Grant nr. R49CE003083) and the National Institute on Aging (NIA) of the National Institutes of Health (NIH) (Grant nr. R01AG090377).
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Doctoral Nursing
- Web of Science ID
- WOS:001869548900001
- Scopus ID
- 2-s2.0-105049554770
- Other Identifier
- 991022197451404721