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Use of gadolinium for carotid artery angiography and stenting in patients with renal insufficiency
Journal article   Peer reviewed

Use of gadolinium for carotid artery angiography and stenting in patients with renal insufficiency

Vamsee Yaganti, Firas Alani, Sushmita Yaganti, Sheldon Goldberg and Daniel McCormick
Journal of renal care, v 35(4), pp 211-218
Dec 2009
PMID: 19909415

Abstract

Aged Aged, 80 and over Angiography - adverse effects Angiography - methods Angioplasty, Balloon - adverse effects Angioplasty, Balloon - methods Carotid Stenosis - complications Carotid Stenosis - diagnostic imaging Carotid Stenosis - therapy Cerebral Angiography - adverse effects Cerebral Angiography - methods Chi-Square Distribution Contrast Media - adverse effects Female Gadolinium DTPA - adverse effects Humans Incidence Iopamidol - adverse effects Kidney Diseases - blood Kidney Diseases - chemically induced Kidney Diseases - epidemiology Length of Stay - statistics & numerical data Male Renal Insufficiency - complications Retrospective Studies Safety Stents Stroke - epidemiology Stroke - etiology Treatment Outcome
Use of iodinated contrast media (ICM) for angiography can result in contrast-induced nephropathy (CIN). Gadolinium-based contrast media (GCM) have been used in angiography with a goal to reduce the incidence of CIN. We performed a retrospective analysis involving 85 patients with renal insufficiency who underwent 97 carotid artery angiography and stenting (CAAS) procedures with a combination of GCM and ICM. The incidence of peri-procedural death, Q wave myocardial infarction (QWMI), stroke and CIN were recorded. Patients in GCM group had worse preprocedure renal function compared to ICM group. There were no peri-procedural deaths or QWMI in both groups. The incidence of stroke was 2.2% in GCM group and 0% in ICM group. The incidence of CIN were similar in GCM and ICM groups (8.5% vs. 10%, respectively, p NS). However, the predicted risk of CIN was 18.5% for GCM group and 10.4% for ICM group. Use of GCM and ICM combination for CAAS resulted in a 50% reduction in the incidence of predicted CIN risk compared to ICM.

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Collaboration types
Domestic collaboration
Web of Science research areas
Nursing
Urology & Nephrology
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