Journal article
Use of the GMFCS in infants with CP: the need for reclassification at age 2 years or older
Developmental medicine and child neurology, v 51(1), pp 46-52
01 Jan 2009
PMID: 19018834
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The stability of the Gross Motor Function Classification System (GMFCS) over time is described in 77 infants (41 boys, 36 girls) with cerebral palsy (CP; mean age 19.4mo [SD 1.6 mo]; 27 unilateral spastic, 42 bilateral spastic, eight dyskinetic type) and in the same children at follow-up at age 2 to 4 years. The overall level of agreement over time (linear weighted kappa) was 0.70 (95% confidence interval [CI] 0.61-0.79). The overall percentage of children whose GMFCS level changed one or two levels was 42%, of which the majority were reclassified to a less functional level (McNemar's Chi(2) test p=0.11). The chance that children initially classified in the combination of GMFCS Levels I, II, and III would subsequently be classified in the same level in early childhood was 96% (positive predictive value [PPV] 0.96, 95% CI 0.85-0.99), whereas the PPV for the combination of Levels I and II was 0.88, 95% CI 0.70-0.96. These findings indicate that GMFCS classification in infants is less precise than classification over time in older children. In conclusion, children can be classified by the GMFCS early on, but there is a need for reclassification at age 2 or older as more clinical information becomes available.
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Details
- Title
- Use of the GMFCS in infants with CP: the need for reclassification at age 2 years or older
- Creators
- Jan Willem Gorter - McMaster UniversityMarjolijn Ketelaar - University Medical Center UtrechtPeter Rosenbaum - McMaster UniversityPaul J. M. Helders - University Medical Center UtrechtRobert Palisano - Drexel University
- Publication Details
- Developmental medicine and child neurology, v 51(1), pp 46-52
- Publisher
- Wiley
- Number of pages
- 7
- Grant note
- MT-13476 / Medical Research Council of Canada; UK Research & Innovation (UKRI); Medical Research Council UK (MRC) R01HD034947 / EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH &HUMAN DEVELOPMENT; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD) ZonMw; Netherlands Organization for Health Research and Development 014-32-034; 14 35.0011 / Netherlands Organization for Health Research and Development R01-HD-34947 / National Institute of Child Health and Human Development at NIH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- [Retired Faculty]
- Web of Science ID
- WOS:000261711500010
- Scopus ID
- 2-s2.0-57949097797
- Other Identifier
- 991019167891204721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Clinical Neurology
- Pediatrics