Journal article
Using new satellite based exposure methods to study the association between pregnancy pm(2.5) exposure, premature birth and birth weight in Massachusetts
Environmental health, v 11, 40
18 Jun 2012
PMID: 22709681
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Background: Adverse birth outcomes such as low birth weight and premature birth have been previously linked with exposure to ambient air pollution. Most studies relied on a limited number of monitors in the region of interest, which can introduce exposure error or restrict the analysis to persons living near a monitor, which reduces sample size and generalizability and may create selection bias.
Methods: We evaluated the relationship between premature birth and birth weight with exposure to ambient particulate matter (PM2.5) levels during pregnancy in Massachusetts for a 9-year period (2000-2008). Building on a novel method we developed for predicting daily PM2.5 at the spatial resolution of a 10x10km grid across New-England, we estimated the average exposure during 30 and 90 days prior to birth as well as the full pregnancy period for each mother. We used linear and logistic mixed models to estimate the association between PM2.5 exposure and birth weight (among full term births) and PM2.5 exposure and preterm birth adjusting for infant sex, maternal age, maternal race, mean income, maternal education level, prenatal care, gestational age, maternal smoking, percent of open space near mothers residence, average traffic density and mothers health.
Results: Birth weight was negatively associated with PM2.5 across all tested periods. For example, a 10 mu g/m(3) increase of PM2.5 exposure during the entire pregnancy was significantly associated with a decrease of 13.80 g [95% confidence interval (CI) = -21.10, -6.05] in birth weight after controlling for other factors, including traffic exposure. The odds ratio for a premature birth was 1.06 (95% confidence interval (CI) = 1.01-1.13) for each 10 mu g/m(3) increase of PM2.5 exposure during the entire pregnancy period.
Conclusions: The presented study suggests that exposure to PM2.5 during the last month of pregnancy contributes to risks for lower birth weight and preterm birth in infants.
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Details
- Title
- Using new satellite based exposure methods to study the association between pregnancy pm(2.5) exposure, premature birth and birth weight in Massachusetts
- Creators
- Itai Kloog - Harvard UniversitySteven J. Melly - Harvard UniversityWilliam L. Ridgway - Science Systems and ApplicationsBrent A. Coull - Harvard UniversityJoel Schwartz - Harvard University
- Publication Details
- Environmental health, v 11, 40
- Publisher
- Springer Nature
- Number of pages
- 8
- Grant note
- Environment and Health Fund (EHF) Israel P30ES000002 / NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Environmental Health Sciences (NIEHS) ES00002; ES012044 / NIH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA R-832416; R83479801 / Harvard Environmental Protection Agency (EPA) Center; United States Environmental Protection Agency
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Urban Health Collaborative
- Web of Science ID
- WOS:000306996400001
- Scopus ID
- 2-s2.0-84864420370
- Other Identifier
- 991021875475304721
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- Collaboration types
- Industry collaboration
- Domestic collaboration
- Web of Science research areas
- Environmental Sciences
- Public, Environmental & Occupational Health