Life Sciences & Biomedicine Obstetrics & Gynecology Science & Technology
Objective. The study aimed to report 2 cases of desquamative inflammatory vaginitis associated with toxic shock syndrome toxin 1 (TSST-1) producing Staphylococcus aureus strains.
Materials and Methods. Case report of 2 patients, 1 with an acute and 1 with a chronic presentation, diagnosed with desquamative inflammatory vaginitis on the basis of clinical findings and wet mount microscopy. Pretreatment and posttreatment vaginal bacterial and yeast cultures were obtained.
Results. Pretreatment vaginal bacterial cultures from both patients grew TSST-1 producing S. aureus. Subsequent vaginal bacterial culture results after oral antibiotic therapy were negative.
Conclusions. Desquamative inflammatory vaginitis may be triggered through TSST-1 mediated vaginal toxic shock reaction.
Nigel Pereira - Drexel Univ, Coll Med, Dept Obstet & Gynecol, Philadelphia, PA 19102 USA
Thomas D. Edlind - Drexel Univ, Coll Med, Dept Microbiol & Immunol, Philadelphia, PA 19102 USA
Patrick M. Schlievert - University of Iowa
Paul Nyirjesy - Drexel University
Publication Details
Journal of lower genital tract disease, v 17(1)
Publisher
Lippincott Williams & Wilkins
Number of pages
4
Grant note
AI-74283; A157153 / USPHS from the NIH
R01AI074283 / NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID)
Resource Type
Journal article
Language
English
Web of Science ID
WOS:000312111300019
Scopus ID
2-s2.0-84871280587
Other Identifier
991019350595504721
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