Journal article
Validation of a BMI cut-off point to predict an adverse cardiometabolic profile with adiposity measurements by dual-energy X-ray absorptiometry in Guatemalan children
Public health nutrition, v 18(6), pp 951-958
Apr 2015
PMID: 24955816
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
To identify a body fat percentage (%BF) threshold related to an adverse cardiometabolic profile and its surrogate BMI cut-off point.
Cross-sectional study.
Two public schools in poor urban areas on the outskirts of Guatemala City.
A convenience sample of ninety-three healthy, prepubertal, Ladino children (aged 7-12 years).
Spearman correlations of cardiometabolic parameters were higher with %BF than with BMI-for-age Z-score. BMI-for-age Z-score and %BF were highly correlated (r=0·84). The %BF threshold that maximized sensitivity and specificity for predicting an adverse cardiometabolic profile (elevated homeostasis model assessment-insulin resistance index and/or total cholesterol:HDL-cholesterol ratio) according to receiver operating characteristic curve analysis was 36 %. The BMI-for-age Z-score cut-off point that maximized the prediction of BF ≥ 36 % by the same procedure was 1·5. The area under the curve (AUC) for %BF and for BMI data showed excellent accuracy to predict an adverse cardiometabolic profile (AUC 0·93 (sd 0·04)) and excess adiposity (AUC 0·95 (sd 0·02)).
Since BMI standards have limitations in screening for adiposity, specific cut-off points based on ethnic-/sex- and age-specific %BF thresholds are needed to better predict an adverse cardiometabolic profile.
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Details
- Title
- Validation of a BMI cut-off point to predict an adverse cardiometabolic profile with adiposity measurements by dual-energy X-ray absorptiometry in Guatemalan children
- Creators
- Olga Redondo - University of AlcaláEduardo Villamor - University of Michigan–Ann ArborJaviera Valdés - Catholic University of the NorthUsama Bilal - Universidad de AlcaláBenjamín Caballero - BloombergDina Roche - Institute of Nutrition of Central America and PanamaFernanda Kroker - Institute of Nutrition of Central America and PanamaManuel Ramírez-Zea - Institute of Nutrition of Central America and PanamaManuel Franco - University of Alcalá
- Publication Details
- Public health nutrition, v 18(6), pp 951-958
- Publisher
- Cambridge University Press
- Grant note
- HHSN26820900032C / PHS HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Urban Health Collaborative
- Web of Science ID
- WOS:000351243900001
- Scopus ID
- 2-s2.0-84924629096
- Other Identifier
- 991019189056704721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Nutrition & Dietetics
- Public, Environmental & Occupational Health