Journal article
Validity of empirical models of exposure in asphalt paving
Occupational and environmental medicine (London, England), v 59(9), pp 620-624
Sep 2002
PMID: 12205236
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Aims:
To investigate the validity of empirical models of exposure to bitumen fume and benzo(a)pyrene, developed for a historical cohort study of asphalt paving in Western Europe.
Methods:
Validity was evaluated using data from the USA, Italy, and Germany not used to develop the original models. Correlation between observed and predicted exposures was examined. Bias and precision were estimated.
Results:
Models were imprecise. Furthermore, predicted bitumen fume exposures tended to be lower (-70%) than concentrations found during paving in the USA. This apparent bias might be attributed to differences between Western European and USA paving practices. Evaluation of the validity of the benzo(a)pyrene exposure model revealed a similar to expected effect of re-paving and a larger than expected effect of tar use. Overall, benzo(a)pyrene models underestimated exposures by 51%.
Conclusions:
Possible bias as a result of underestimation of the impact of coal tar on benzo(a)pyrene exposure levels must be explored in sensitivity analysis of the exposure–response relation. Validation of the models, albeit limited, increased our confidence in their applicability to exposure assessment in the historical cohort study of cancer risk among asphalt workers.
Metrics
Details
- Title
- Validity of empirical models of exposure in asphalt paving
- Creators
- I Burstyn - Division of Environmental and Occupational Health, Institute for Risk Assessment Sciences, Utrecht University, PO Box 80176, 3508 TD Utrecht, NetherlandsP Boffetta - Division of Environmental and Occupational Health, Institute for Risk Assessment Sciences, Utrecht University, PO Box 80176, 3508 TD Utrecht, NetherlandsG Burr - Division of Environmental and Occupational Health, Institute for Risk Assessment Sciences, Utrecht University, PO Box 80176, 3508 TD Utrecht, NetherlandsA Cenni - Division of Environmental and Occupational Health, Institute for Risk Assessment Sciences, Utrecht University, PO Box 80176, 3508 TD Utrecht, NetherlandsU Knecht - Division of Environmental and Occupational Health, Institute for Risk Assessment Sciences, Utrecht University, PO Box 80176, 3508 TD Utrecht, NetherlandsG Sciarra - Division of Environmental and Occupational Health, Institute for Risk Assessment Sciences, Utrecht University, PO Box 80176, 3508 TD Utrecht, NetherlandsH Kromhout - Division of Environmental and Occupational Health, Institute for Risk Assessment Sciences, Utrecht University, PO Box 80176, 3508 TD Utrecht, Netherlands
- Publication Details
- Occupational and environmental medicine (London, England), v 59(9), pp 620-624
- Publisher
- BMJ Group
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Environmental and Occupational Health
- Web of Science ID
- WOS:000177957200008
- Scopus ID
- 2-s2.0-0036360701
- Other Identifier
- 991014878019604721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Public, Environmental & Occupational Health