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Variations among Sublines of Inbred AKR Mice
Journal article

Variations among Sublines of Inbred AKR Mice

RONALD T Acton, ELIZABETH P Blankenhorn, TOMMY C Douglas, RAY D Owen, J O Hilgers, HAROLD A Hoffman and EDWARD A Boyse
Nature. New biology (London), v 245(140), pp 8-10
05 Sep 1973
PMID: 4353891

Abstract

THE AKR inbred line of mice, developed as a strain with a high incidence of leukaemia, has found wide use in the fields of genetics, immunology, virology, and cancer research. While a certain degree of variability is expected among sublines derived from any inbred strain, rather striking differences have been observed among AKR sublines. Because such differences can be crucial to the usefulness of AKR mice for biomedical research, observations regarding some of these AKR sublines have been collected from several laboratories.

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