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Vascular Inflammation, Cancer, and Cardiovascular Diseases
Journal article   Peer reviewed

Vascular Inflammation, Cancer, and Cardiovascular Diseases

George S Prousi, Amogh M Joshi, Varun Atti, Daniel Addison, Sherry-Ann Brown, Avirup Guha and Brijesh Patel
Current oncology reports, v 25(9), pp 955-963
01 Sep 2023
DOI: https://doi.org/10.1007/s11912-023-01426-0
PMID: 37261651
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://pmc.ncbi.nlm.nih.gov/articles/PMC12258637/pdf/nihms-2007626.pdfView
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Abstract

Cardiotoxicity - etiology Cardiovascular Diseases - therapy Humans Inflammation - complications Neoplasms - therapy Signal Transduction
Cancer and cardiovascular disease are among the leading causes of morbidity and mortality in the USA. Cancer and cardiovascular disease have inflammatory underpinnings that have been associated with both the development and progression of these disease states. Inflammatory signaling has been found to be a critical event in both cardiovascular disease and cancer formation and progression. Further, many chemotherapeutic agents potentiate inflammation exacerbating existing cardiovascular disease or leading to its presence. The exact mechanisms of these interactions remain poorly understood. The proinflammatory milieu observed in both cancer and cardiovascular disease likely plays an important role in the development and potentiation of both conditions. Further evaluation of this relationship will be critical in the development of new diagnostic and therapeutic modalities.

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Collaboration types
Domestic collaboration
Web of Science research areas
Oncology
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