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Vedolizumab-Associated Primary Cutaneous CD4+ Small/Medium T-Cell Lymphoproliferative Disorder in a Biologic-Naïve Pediatric Patient With Crohn's Disease
Journal article   Open access   Peer reviewed

Vedolizumab-Associated Primary Cutaneous CD4+ Small/Medium T-Cell Lymphoproliferative Disorder in a Biologic-Naïve Pediatric Patient With Crohn's Disease

Romina Garakani, Zane Sejdiu, Devon Cross, Hassan Abdullah, Farhaan Hafeez and Andrew C. Krakowski
Pediatric dermatology, v 43(3), pp 781-782
01 May 2026
PMID: 41717667
url
https://doi.org/10.1111/pde.70169View
Published, Version of Record (VoR) Open Maybe Open Access (Publisher Bronze)

Abstract

Primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder (PCSM-TCLPD) is a rare lymphoproliferative disorder that is occasionally diagnosed in children and adolescents. We present a case of PCSM-TCLPD in an 11-year-old female with biologic-naïve Crohn's disease well-controlled on vedolizumab, which was initiated 12 months prior to lesion appearance. We propose that vedolizumab may have played a role in the development of PCSM-TCLPD.

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Web of Science research areas
Dermatology
Pediatrics
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