Journal article
Ventricular arrhythmias: Use of electrophysiologic studies
The American heart journal, v 106(4), pp 881-886
1983
PMID: 6613834
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The clinical utility of electrophysiologic testing in assessing the long-term efficacy of amiodarone for treatment of life-threatening ventricular arrhythmias is controversial, most investigators reporting little or no correlation between the early effects of the drug on arrhythmia inducibility and subsequent prognosis. We have evaluated 69 consecutive patients given amiodarone for ventricular tachycardia (VT) or fibrillation (VF). All patients underwent provocative electrophysiologic testing with programmed electrical stimulation before and after amiodarone loading. After a standardized amiodarone loading regimen, the patients' arrhythmias were not inducible in 22 patients (group 1) and remained inducible in 47 patients (group 2). No patient in group 1 has had a recurrence of
VT
VF
, whereas 15 (32%) of 47 patients in group 2 have had recurrences. The characteristics of the arrhythmia induced by programmed stimulation in group 2 accurately predicted the severity of the recurrence. We conclude that electrophysiologic testing may be useful in evaluating the efficacy of amiodarone for the long-term treatment of
VT
VF
and that its precise role in this context should be further investigated by stringently controlled studies.
Metrics
Details
- Title
- Ventricular arrhythmias: Use of electrophysiologic studies
- Creators
- Leonard N. Horowitz - Hahnemann University HospitalScott R. Spielman - Hahnemann University HospitalAllan M. Greenspan - Hahnemann University HospitalCharles R. Webb - Hahnemann University HospitalHarold R. Kay - Hahnemann University Hospital
- Publication Details
- The American heart journal, v 106(4), pp 881-886
- Publisher
- Mosby, Inc
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- College of Medicine
- Web of Science ID
- WOS:A1983RK66000011
- Scopus ID
- 2-s2.0-0020627274
- Other Identifier
- 991019339571804721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Cardiac & Cardiovascular Systems