Journal article
Verbal Learning and Memory in Older Adults with Minor and Major Depression
Archives of clinical neuropsychology, v 27(2)
21 Dec 2011
PMID: 22189596
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Late-life minor depression (miD) is a prevalent but poorly understood illness. Verbal learning and memory profiles have commonly been used to characterize neuropsychiatric disorders. This study compared the performance of 27 older adults with miD on the California Verbal Learning Test (CVLT) with 26 age-matched individuals with Major Depressive Disorder (MDD) and 36 non-depressed controls. Results revealed that the miD group performed comparably with controls and significantly better than the MDD group on several CVLT indices. Moreover, cluster analysis revealed three distinct groups, consistent with theoretical representations of “normal,” “subcortical,” and “cortical” verbal learning and memory profiles. The majority of the miD group showed “normal” profiles (74%), whereas most individuals with MDD displayed “subcortical” profiles (54%). The findings suggest that depression in the elderly is a heterogeneous entity and that the CVLT may be a useful tool for characterizing learning and memory in late-onset depressive disorders.
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Details
- Title
- Verbal Learning and Memory in Older Adults with Minor and Major Depression
- Creators
- Raquelle I. Mesholam-Gately - Beth Israel Deaconess Medical CenterAnthony J. Giuliano - Beth Israel Deaconess Medical CenterEric A. Zillmer - Drexel UniversityLamia P. Barakat - University of PennsylvaniaAnand Kumar - University of Illinois at ChicagoRuben C. Gur - University of PennsylvaniaLisa M. McAndrew - Veterans Health AdministrationWarren B. Bilker - University of PennsylvaniaVirginia Elderkin-Thompson - Semel Institute for Neuroscience and Human BehaviorPaul J. Moberg - University of Pennsylvania
- Publication Details
- Archives of clinical neuropsychology, v 27(2)
- Publisher
- Oxford University Press
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Psychological and Brain Sciences (Psychology)
- Web of Science ID
- WOS:000300486900009
- Scopus ID
- 2-s2.0-84862267929
- Other Identifier
- 991019168181304721
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Psychology
- Psychology, Clinical