Life Sciences & Biomedicine Ophthalmology Science & Technology
Purpose
To evaluate the association between outdoor and nearwork activities at baseline and myopia stabilisation by age 15 in the Correction of Myopia Evaluation Trial (COMET).
Methods
Correction of Myopia Evaluation Trial enrolled 469 children (ages: 6-11years) with spherical equivalent myopia between -1.25 and -4.50D, who were randomised to progressive addition or single vision lenses and followed for 5years in their original lenses. At baseline, families recorded the child's outdoor and nearwork activities for 3days within a week. Weekly hours spent in nearwork and outdoor activities were calculated for each participant. Refractions collected over 11years were fit using the Gompertz function to determine each participant's myopia stabilisation age. Myopia for each child was then categorized as stable/not stable by age 15.
Results
Half (233/469) of participants had usable baseline activity diaries and refraction data that could be fit with the Gompertz function, 59.7% (139/233) had stable myopia by age 15 and 40.3% had myopia that was not yet stable. The frequency of stable myopia was similar for the two categories (median split) of outdoor activities: 60% (71/118) for <= 9.0hours/week(-1) and 59% (68/115) for >9.0hours/week(-1). 56% (64/114) of children reporting >21.0h of baseline weekly nearwork activity had stable myopia by age 15 compared to 63% (75/119) with <= 21.0h of near work (adjusted OR=0.74; 95% CI: 0.43-1.29). Using baseline nearwork as a continuous variable, the multivariable odds ratio for the association between baseline nearwork hours and stabilisation by age 15 is 0.98: 95% CI: 0.96-1.00, a result trending towards significance.
Conclusion
While time spent in outdoor activities in childhood does not appear to be related to myopia stabilisation by age 15, less near work activity might potentially be associated with myopia stabilisation by that age.
Visual activity and its association with myopia stabilisation
Creators
Mitchell Scheiman - Salus University
Qinghua Zhang - Stony Brook University Hospital
Jane Gwiazda - New England College of Optometry
Leslie Hyman - Stony Brook University Hospital
Elise Harb - New England College of Optometry
Erik Weissberg - New England College of Optometry
Katherine K. Weise - University of Alabama at Birmingham
Lynette Dias - Stony Brook University Hospital
COMET Study Grp
Publication Details
Ophthalmic & physiological optics, v 34(3), pp 353-361
Publisher
Wiley
Number of pages
9
Grant note
EY11756; EY11754; EY11805; EY11752; EY11740; EY11755 / National Eye Institute, National Institute of Health, Department of Health and Human Services, NEI/NIH grants
U10EY014713 / NATIONAL EYE INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Eye Institute (NEI)
Resource Type
Journal article
Language
English
Academic Unit
Pennsylvania College of Optometry (PCO)
Web of Science ID
WOS:000334924500008
Scopus ID
2-s2.0-84899490997
Other Identifier
991021900610704721
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Collaboration types
Domestic collaboration
Web of Science research areas
Ophthalmology
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