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Vitamin D receptor genotype is not associated with bone mineral density in three ethnic/regional groups
Journal article   Peer reviewed

Vitamin D receptor genotype is not associated with bone mineral density in three ethnic/regional groups

L D Spotila, J Caminis, R Johnston, K S Shimoya, M P O'Connor, D J Prockop, A Tenenhouse and H S Tenenhouse
Calcified tissue international, v 59(4), pp 235-237
Oct 1996
DOI: https://doi.org/10.1007/s002239900114
PMID: 8781043
Featured in Collection :   UN Sustainable Development Goals @ Drexel

Abstract

Bone Density - genetics Female Humans Male Postmenopause Premenopause Quebec - ethnology Receptors, Calcitriol - genetics
We report a cross-sectional study of 48 men, 56 premenopausal women, and 80 postmenopausal women who were of three ethnic/regional backgrounds: southern European (Greek, Italian), eastern European (Jewish, Polish, Hungarian), and western European (French, British). We determined bone mineral density (BMD) at four skeletal sites and assessed the vitamin D receptor (VDR) genotype by the Bsml restriction site polymorphism. Age and body mass index had significant effects on BMD by multiple regression analysis. In addition, ethnic/regional group had a significant effect on spinal BMD in premenopausal females (P = 0.014) and in males (P = 0.039). However, VDR genotype had no significant effect on BMD in any of the three study groups.

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29 citations in Web of Science
33 citations in Scopus

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UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#5 Gender Equality
#3 Good Health and Well-Being

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Collaboration types
Domestic collaboration
International collaboration
Web of Science research areas
Endocrinology & Metabolism
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