Journal article
Vocal Fold Augmentation with Calcium Hydroxylapatite: Twelve-Month Report
The Laryngoscope, v 119(5), pp 1033-1041
01 May 2009
PMID: 19274731
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Objectives: To evaluate the long-term effectiveness of calcium hydroxylapatite (CaHA) vocal fold injection for patients with glottal insufficiency.
Study Design: Multicenter, open-label, prospective clinical study of CaHA vocal fold injection.
Methods: Each patient served as his/her own control. Voice-related outcome measures were collected for pre-injection, 1, 3, 6, and 12 months.
Results: Sixty-three patients were available for evaluation. Fifty-three percent of the injection procedures were done in the office. Fifty-seven percent of patients were diagnosed with unilateral paralysis and 43% with glottal incompetence with mobile vocal folds. Patient satisfaction 12 months after injection showed 67% reporting a significant improvement in voice and 81% reporting at least a moderate improvement in voice. Utilizing the Voice Handicap Index-10, visual analog scale (vocal effort), Consensus Assessment Perceptual Evaluation V (judgments of voice severity), and objective voice measures of glottal closure (maximum phonation time and S:Z ratio), paired t tests showed significant improvements after treatment. A 22% further treatment rate was found at the 12-month time point.
Conclusions: One-year results in this large cohort of patients with glottal incompetence treated with CaHA vocal fold injection demonstrate that excellent clinical results were achieved.
Metrics
Details
- Title
- Vocal Fold Augmentation with Calcium Hydroxylapatite: Twelve-Month Report
- Creators
- Clark A. Rosen - University of PittsburghJackie Gartner-Schmidt - University of PittsburghRoy Casiano - University of MiamiTimothy D. Anderson - Lahey Hospital and Medical CenterFelicia Johnson - University of Arkansas for Medical SciencesMarc Remacle - Université Catholique de LouvainRobert T. Sataloff - Drexel UniversityJean Abitbol - Assistance Publique – Hôpitaux de ParisGary Shaw - Kansas City University of Medicine and BiosciencesSanford Archer - University of KentuckyRichard I. Zraick - University of Arkansas at Little Rock
- Publication Details
- The Laryngoscope, v 119(5), pp 1033-1041
- Publisher
- Wiley
- Number of pages
- 9
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- College of Medicine
- Web of Science ID
- WOS:000265866000032
- Scopus ID
- 2-s2.0-66349085906
- Other Identifier
- 991019312384504721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Medicine, Research & Experimental
- Otorhinolaryngology