Journal article
Vocal fold augmentation with calcium hydroxylapatite (CaHA)
Otolaryngology-head and neck surgery, v 136(2), pp 198-204
Feb 2007
PMID: 17275539
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Objectives
Evaluate the effectiveness of CaHA injection for patients with glottal incompetence.
Methods
Multi-center, open-label, prospective clinical study with each patient serving as his/her own control. Voice-related outcome measures were collected for pre-injection and 1, 3, and 6 months.
Results
Sixty-eight patients were available for evaluation. Fifty percent of the injection procedures were done in office. Fifty-seven percent were diagnosed with unilateral paralysis and 42% with glottal incompetence with mobile vocal folds. Patient satisfaction 6 months post showed 56% had significantly improved voice and 38% reported moderately improved voice. Paired t tests from baseline to 6 months showed significant improvements on the VHI and VAS (vocal effort), CAPE-V judgments of voice severity and videoendostroboscopy ratings of glottal closure, and objective voice measures of glottal closure (MPT and S:Z ratio).
Conclusions
Preliminary results in this large cohort of patients demonstrate excellent clinical results.
Metrics
Details
- Title
- Vocal fold augmentation with calcium hydroxylapatite (CaHA)
- Creators
- Clark A. Rosen - From the University of Pittsburgh Dept. of Otolaryngology-HNS, University of Pittsburgh Voice Center, Pittsburgh, PAJackie Gartner-Schmidt - From the University of Pittsburgh Dept. of Otolaryngology-HNS, University of Pittsburgh Voice Center, Pittsburgh, PARoy Casiano - University of Pittsburgh Voice Center, Pittsburgh, PA, University of Miami Medical Center, Miami, FLTimothy D. Anderson - Lahey Hospital and Medical CenterFelicia Johnson - University of Arkansas Dept of Otolaryngology, Little Rock, ARLee Reussner - Kansas Voice Center, Lawrence, KSMarc Remacle - University Hospital of Louvain-Mont Goddine, Yvoir, BelgiumRobert T. Sataloff - Philadelphia ENT Associates, Philadelphia, PAJean Abitbol - University of Paris, Paris, FranceGary Shaw - Private Practice, Lees Summit, MOSanford Archer - University of Kentucky Dept of Otolaryngology, Lexington, KYAndrew McWhorter - Louisiana State University Health Sciences Center, Dept of Otolaryngology, New Orleans, LA
- Publication Details
- Otolaryngology-head and neck surgery, v 136(2), pp 198-204
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- College of Medicine
- Web of Science ID
- WOS:000244052200007
- Scopus ID
- 2-s2.0-33846698539
- Other Identifier
- 991019312610904721
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Otorhinolaryngology
- Surgery