Journal article
Vulnerability to the Cardiovascular Effects of Ambient Heat in Six US Cities: Results from the Multi-Ethnic Study of Atherosclerosis (MESA)
Epidemiology (Cambridge, Mass.), v 29(6), pp 756-764
Nov 2018
PMID: 30113342
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
With climate change, temperatures are increasing. Heat-associated health events disproportionately affect certain subpopulations. However, prior research has often lacked information on individual-level health and air conditioning and neighborhood stressors/protections.
To assess whether (1) heat (2-day mean temperature above local 75th percentiles) is associated with increased heart rate and decreased blood pressure, controlling for age, time, season, daily ozone, and daily particulate matter (PM2.5) and (2) associations differ by antihypertensive medication use, renal function, fasting glucose, emotional support, air conditioning ownership and use, normalized difference vegetation index, neighborhood safety, and residence- specific oxides of nitrogen and PM2.5.
Health and behavioral characteristics were obtained repeatedly on participants of the Multi-Ethnic Study of Atherosclerosis in six US sites (2000-2010). These were linked with airport temperature, air quality, and satellite- and survey-derived neighborhood characteristics. We used a fixed-effects design, regressing health outcomes on linear temperature splines with knots at the 75th percentiles, interaction terms for each characteristic, and adjustment for month of year, age, PM2.5, and ozone.
Overall, heat was not associated with heart rate. However, for a 2°C increase in heat, systolic blood pressure decreased by 1.1 mmHg (95% CI = -1.6, -0.6) and diastolic blood pressure by 0.3 mmHg (95% CI = -0.6, -0.1). Among nonusers of antihypertensive medications, heat-associated decreases in SBP were 2.1 mmHg greater among individuals with central air conditioning versus those without. Confidence intervals around the remaining modifiers were wide after multiple-comparisons corrections or sensitivity analyses.
Outdoor heat is associated with decreasing blood pressure, and cardiovascular vulnerability may vary primarily by ownership of central air conditioning.
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Details
- Title
- Vulnerability to the Cardiovascular Effects of Ambient Heat in Six US Cities: Results from the Multi-Ethnic Study of Atherosclerosis (MESA)
- Creators
- Carina J Gronlund - University of Michigan–Ann ArborLianne Sheppard - University of WashingtonSara D Adar - University of Michigan–Ann ArborMarie S O'Neill - University of Michigan–Ann ArborAmy Auchincloss - Drexel UniversityJaime Madrigano - RAND CorporationJoel Kaufman - University of WashingtonAna V Diez Roux - Drexel University
- Publication Details
- Epidemiology (Cambridge, Mass.), v 29(6), pp 756-764
- Publisher
- Lippincott
- Grant note
- N01HC95169 / NHLBI NIH HHS N01HC95161 / NHLBI NIH HHS T42 OH008455 / NIOSH CDC HHS N01HC95164 / NHLBI NIH HHS UL1 TR002240 / NCATS NIH HHS HHSN268201500003C / NHLBI NIH HHS N01HC95160 / NHLBI NIH HHS K99 ES026198 / NIEHS NIH HHS UL1 TR000433 / NCATS NIH HHS N01HC95167 / NHLBI NIH HHS N01HC95159 / NHLBI NIH HHS N01HC95163 / NHLBI NIH HHS N01HC95166 / NHLBI NIH HHS N01HC95168 / NHLBI NIH HHS UL1 TR000040 / NCATS NIH HHS UL1 TR001079 / NCATS NIH HHS N01HC95165 / NHLBI NIH HHS P30 ES017885 / NIEHS NIH HHS N01HC95162 / NHLBI NIH HHS UL1 TR001420 / NCATS NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Urban Health Collaborative; Epidemiology and Biostatistics
- Web of Science ID
- WOS:000446681600015
- Scopus ID
- 2-s2.0-85055616297
- Other Identifier
- 991019168574204721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Public, Environmental & Occupational Health